Patterns that pay rent
The Dispatch tasks that justify the setup investment all share three properties: they happen often (daily/weekly), they're verifiable (you can tell if the output is right at a glance), and they free attention (the time saved isn't replaced with checking the result). Optimize for those three.
Anti-patterns to avoid: using Dispatch as a one-shot reminder (just use Reminders.app), using Dispatch for tasks that need iteration (Cowork at the desk), chaining 5 dependent Dispatch tasks at once (you'll lose track — break into smaller pieces or run live), Dispatch + risky permissions (SendEmail + open-ended task = bad day).